physician scientist
University of Washington
Seattle, United States
Dr. Jill Johnsen is an Associate Professor at the University of Washington and practices at the Washington Center for Bleeding Disorders. She is a physician scientist with expertise in classical (benign) hematology and studies the genetics and biology of variation in clotting factors and blood groups (blood types), with emphasis on coagulation factor VIII, factor IX, and von Willebrand factor. Dr. Johnsen's overall program is dedicated to improving the diagnosis and care of patients with blood disorders through advancement of our basic understanding of the underlying biology and through the translation of new knowledge and laboratory innovations to improve clinical testing. She is particularly focused on research that will help better understand of how bleeding impacts females. Her research leverages new technologies, including targeted and whole genome next generation DNA sequencing, multi-omics, long-read sequencing, and new and novel molecular methods. In vitro functional studies, including large scale deep mutational scanning of genes of interest in mammalian cell display systems, will inform and improve interpretation of the functional significance of DNA variants discovered in hemophilia.